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She mentioned the research "reinforces WHO’s recently revised position on HPV vaccination". Prof Brisson, from Laval University, Canada, said "it might be crucial" now to proceed to monitor the impacts of vaccination programmes. However the findings should not be extrapolated to low and center-income nations the place the burden of disease was far higher, the staff warned. Their analysis also found there have been better and faster impacts, and herd effects, in nations with each multi-cohort vaccination and high vaccination protection. Anogenital wart diagnoses declined by 88% amongst women and 86% in boys aged 15-19 in these international locations, compared with 44% and 1% respectively in international locations with single-cohort or low protection. Likewise, after five to eight years of vaccination, precancerous cervical lesions decreased by 57% in girls aged 15 to 19, whereas there was no decrease in nations with single-cohort vaccination or low routine protection. Professor Silvia de Sanjose, from the trail organisation in the USA, stated optimising HPV vaccination programmes could make it "a hallmark investment of cancer prevention in the twenty first century".

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